Breast Cancer

Trial Add-Aspirin Trial
Cancer Type Breast Cancer and Miscellaneous
Hospital(s) Belfast City Hospital and Craigavon Hospital
Information

A Phase III, Double-Blind, Placebo-Controlled Randomised Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival after Primary Therapy in Common Non-Metastatic Solid Tumours

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Trial ANTHEM
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

The ANTHEM Feasibility Study, Is A Novel THErapeutic mammaplasty procedure a safe and effective alternative to Mastectomy for treatment of breast cancer?

Trial ASTEFANIA
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A phase III, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of adjuvant atezolizumab or placebo and trastuzumab emtansine for her2-positive breast cancer at high risk of recurrence following preoperative therapy

Trial ATNEC
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases
at presentation after neoadjuvant chemotherapy

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Trial EndoNET
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital and Belfast City Hospital
Information

Randomised controlled trial evaluating effectiveness of neoadjuvant endocrine treatment in post-menopausal women

Trial IMPARTER:4
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

IMproving PAtient undeRstanding of GEP TEst Results: Phase 4

Trial KEYNOTE-B49
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

A Randomised, Double-blind, Placebo-controlled, Phase 3 Study of Pembrolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy for the Treatment of Chemotherapy-Candidate Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (HR+/HER2-) Metastatic Breast Cancer

Trial MARECA
Cancer Type Breast Cancer
Hospital(s) Antrim Hospital
Information

National study of management of breast cancer locoregional recurrence and oncologic outcome

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Trial MARECA
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital, Belfast City Hospital, and Craigavon Hospital
Information

National study of management of breast cancer locoregional recurrence and oncological outcome

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Trial NOSTRA
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A prospective, non-randomised, multi-centre feasibility study to assess if patients residual cancer following dual-targeted neoadjuvant chemotherapy treatment for HER2-positive, ER-negative early breast cancer can be identified by multiple ultrasound-guided tumour bed core biopsies

Trial OPTIMA
Cancer Type Breast Cancer
Hospital(s) Ulster Hospital
Information

Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis

Trial PEARL
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A window of opportunity study to assess the biological effects of progesterone in premenopausal ER-positive, PgR-positive early breast cancer

Trial POETIC-A
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Pre-Operative Endocrine Therapy for Individualised Care with Abemaciclib

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Trial SMALL Trial
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital, Belfast City Hospital, and Craigavon Hospital
Information

A Phase III, randomised, multi-centre trial addressing overtreatment of small screen-detected breast cancer by comparing standard surgery versus minimally invasive vacuum-assisted excision

Trial TROPION - 03
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator’s Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy (TROPION-Breast03)