Breast Cancer

Trial ANTHEM
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

The ANTHEM Feasibility Study, Is A Novel THErapeutic mammaplasty procedure a safe and effective alternative to Mastectomy for treatment of breast cancer?

Trial ASTEFANIA
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A phase III, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of adjuvant atezolizumab or placebo and trastuzumab emtansine for her2-positive breast cancer at high risk of recurrence following preoperative therapy

Trial ATNEC
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Axillary management in T1-3N1M0 breast cancer patients with needle biopsy proven nodal metastases
at presentation after neoadjuvant chemotherapy

Click Here to view CancerHelpUK trial summary
Trial EndoNET
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Randomised controlled trial evaluating effectiveness of neoadjuvant endocrine treatment in post-menopausal women

Trial IMPARTER:4
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

IMproving PAtient undeRstanding of GEP TEst Results: Phase 4

Trial KEYNOTE-B49
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

A Randomised, Double-blind, Placebo-controlled, Phase 3 Study of Pembrolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy for the Treatment of Chemotherapy-Candidate Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (HR+/HER2-) Metastatic Breast Cancer

Trial MARECA
Cancer Type Breast Cancer
Hospital(s) Antrim Hospital
Information

National study of management of breast cancer locoregional recurrence and oncologic outcome

Click Here to view CancerHelpUK trial summary
Trial MARECA
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

National study of management of breast cancer locoregional recurrence and oncological outcome

Click Here to view CancerHelpUK trial summary
Trial NERELYFE Study
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

Multicenter, multi-country, prospective, observational, post authorisation safety study to describe the incidence of discontinuation due to diarrhoea within the first 3 months of treatment with neratinib, in adult breast cancer patients treated in extended adjuvant in a real world setting: the NERLYFE study. Ancillary study: A Nerlyfe ancillary study to describe recurrence in breast cancer patients treated with neratinib in a real-world setting

Trial NOSTRA
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A prospective, non-randomised, multi-centre feasibility study to assess if patients residual cancer following dual-targeted neoadjuvant chemotherapy treatment for HER2-positive, ER-negative early breast cancer can be identified by multiple ultrasound-guided tumour bed core biopsies

Trial OPTIMA
Cancer Type Breast Cancer
Hospital(s) Ulster Hospital
Information

Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis

Trial PEARL
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

A window of opportunity study to assess the biological effects of progesterone in premenopausal ER-positive, PgR-positive early breast cancer

Trial POETIC-A
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Pre-Operative Endocrine Therapy for Individualised Care with Abemaciclib

Click Here to view CancerHelpUK trial summary
Trial RESTORE-C19
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Exploring the experiences and outcomes of patients not offered immediate breast REconstruction after maSTectOmy for bREast cancer during the COVID-19 pandemic

Trial ROSCO
Cancer Type Breast Cancer
Hospital(s) Belfast City Hospital
Information

Response To Optimal Selection Of Neo-Adjuvant Chemotherapy In Operable Breast Cancer

Trial SMALL Trial
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital, Belfast City Hospital, and Craigavon Hospital
Information

A Phase III, randomised, multi-centre trial addressing overtreatment of small screen-detected breast cancer by comparing standard surgery versus minimally invasive vacuum-assisted excision

Trial TROPION - 03
Cancer Type Breast Cancer
Hospital(s) Altnagelvin Hospital
Information

A Phase 3 Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Versus Investigator’s Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Who Have Residual Invasive Disease in the Breast and/or Axillary Lymph Nodes at Surgical Resection Following Neoadjuvant Systemic Therapy (TROPION-Breast03)