Results of the FAST-Forward study of radiotherapy for breast cancer

The NI Cancer Trials Network at Belfast Trust was one of several centres in the UK involved in the FAST-Forward study of radiotherapy for women following surgery for early breast cancer.

Between 2011 and 2014 over 4000 participants were randomly assigned to one of 3 arms:

  • 40Gy in 15 fractions (over 3 weeks – standard of care)
  • 27Gy in 5 fractions (over 1 week)
  • 26Gy in 5 fractions (over 1 week)

Five-year results are now published in the Lancet revealing a one-week course of radiotherapy in fewer but larger doses is as safe and effective as the standard three-week therapy.  Researchers have already seen a change in practice, reducing hospital visits for patients during the COVID-19 pandemic as well as reducing demands on the health service.  Read more here.

Massive thanks to the staff and patients in Northern Ireland for their contribution to this study.

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